Superculture® Pet Immune:For occasional itching and skin & coat health
Clinically validated to reduce itching and improve skin & coat health in healthy pets
Order a Sample →
Key Outcomes from 2 Clinical Studies

- >2.5x more effective at reducing itching than other clinically studied biotics for pets.1
- Clinically shown to reduce itching behavior by 20%, quantified by a wearable activity monitor.1
- Clinically shown to improve human perception of itching behavior in just 14 days.1
- Clinically shown to improve human perception of coat quality in just 14 days.1
- Clinically shown to improve coat softness and glossiness at Day 56 and Day 91, demonstrating sustained skin & coat benefits. 2
- Double-blind, placebo-controlled study Superculture® Pet Immune, conducted 11-2024
- Double-blind, placebo-controlled study Superculture® Pet Immune, conducted 06- through 09-2025
How Superculture® Pet Immune Measures Up
Other INgredients
Others
Itching reduction (human perception)
In 14 days
No statistically significant data
Itching reduction (wearable activity monitor)
In 28 days
No data
Visible skin & coat improvement
In 14 days
No statistically significant data
Sustained improvements in coat softness and glossiness
At days 56 and 91
No statistically significant data
The Unmet Health Need
- Itching and skin & coat health are amongst pet parents' biggest concerns.
- Skin allergies have been the #1 reason for vet visits for 13 consecutive years for dogs. Itching is among the most-searched and most-discussed pet immune concerns, yet pet parents consistently report that existing products don’t bring relief.
- Yet current solutions fail to address these interconnected immune challenges by systemically influencing the immune system and the gut microbiome.
Our Key Insight
- Indole compounds are uniquely produced by a healthy gut microbiome, circulate systemically throughout the body, and elicit a wide range of positive health benefits across the gut, skin, and immune system.
- They constitute an important and previously unharnessed modality for addressing itching and other challenging skin and immune needs in pets.
Our Development Process
- Through high-throughput screening of our proprietary biobank, we identified microbial strains with exceptional indole metabolism capabilities.
- We optimized the fermentation process to maximize beneficial indole yields while ensuring stability.
- We then validated the ingredient’s efficacy in two double-blinded, placebo-controlled clinical studies.
- The result: industry-leading efficacy across itching and skin health in just a few weeks.
Ingredient Composition
Made from natural, non-GMO microbial strains.
Dried Pediococcus acidilactici fermentation product
Covered by AAFCO definitions and included on the EU QPS list See Tech Spec Sheet
Ingredient Labeling Suggestions
The ingredient is often labeled as:
- Dried Pediococcus acidilactici fermentation product
- Postbiotic (Pediococcus acidilactici)
- [Canine/Feline] Immune Health Postbiotic
- [Canine/Feline] Immune Health Fermentate
- [Canine/Feline] Skin Health Postbiotic
- [Canine/Feline] Skin Health Fermentate
Superculture® Pet Immune in Industry Publications

PEER-REVIEWED
An indole-rich postbiotic reduces itching in dogs: a randomized, double-blinded placebo-controlled study
Read More

PRESENTATION
QC Best Practices for Consistency and Efficacy in Pre-, Post- and Probiotics
