Superculture® Pet Immune
Clinically validated to address occasional itching, skin/coat health, and digestive wellness in dogs
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Key Outcomes from 3 Clinical Studies
- >2.5x more effective at reducing itching than other clinically studied biotics for pets.1
- Clinically shown to reduce itching behavior by 20%, quantified by a wearable activity monitor. 1
- Clinically shown to improve human perception of itching behavior in just 14 days.1
- Clinically shown to increase gut microbiome Shannon diversity.1,2
- Clinically shown to improve stool quality in just 28 days.2
- Clinically shown to improve coat softness and glossiness. 3
- Double-blind, placebo-controlled study Superculture® Pet Immune, conducted 11-2024
- Double-blind, placebo-controlled study Superculture® Pet Immune, conducted 05-2025
- Double-blind, placebo-controlled study Superculture® Pet Immune, conducted 06- through 09-2025
How Superculture® Pet Immune Measures Up
Other INgredients
Others
Itching reduction (human perception)
In 14 days
No statistically significant data
Itching reduction (wearable activity monitor)
In 28 days
No data
Visible skin & coat improvement
In 14 days
No statistically significant data
Stool quality improvement
In 28 days
None, some worsen stool quality
Increased gut microbiome diversity
In 28 days
No statistically significant data
The Unmet Health Need
- Immune health drives pet parents' biggest concerns.
- Skin allergies have been the #1 reason for vet visits for 11 consecutive years, and over 90% of owners say gut health is a critical need.
- Yet current solutions fail to address these interconnected immune challenges by systemically influencing the immune system and the gut microbiome.
Our Key Insight
- Indole compounds are uniquely produced by a healthy gut microbiome, circulate systemically throughout the body, and elicit a wide range of positive health benefits.
- They constitute an important and previously unharnessed modality for addressing itching and other challenging skin and immune conditions in pets.
Our Development Process
- Through high-throughput screening of our proprietary biobank, we identified microbial strains with exceptional indole metabolism capabilities.
- We optimized the fermentation process to maximize beneficial indole yields while ensuring stability.
- Three double-blinded, placebo-controlled clinical studies validate the ingredient's efficacy across multiple health endpoints.
- The result: industry-leading efficacy across itching, skin, and gut health in just a few weeks.
Ingredient Composition
Made from natural, non-GMO microbial strains.
Dried Pediococcus acidilactici fermentation product
Covered by AAFCO definitions and included on the EU QPS list See Tech Spec Sheet
Ingredient Labeling Suggestions
The ingredient is often labeled as:
- Postbiotic (Pediococcus acidilactici)
- Canine Immune Health Postbiotic
- Canine Immune Health Fermentate
Superculture® Pet Immune in Industry Publications
PEER-REVIEWED
An indole-rich postbiotic reduces itching in dogs: a randomized, double-blinded placebo-controlled study
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PRESENTATION
QC Best Practices for Consistency and Efficacy in Pre-, Post- and Probiotics